Preclinical Safety Expert (m/f/d)

Preclinical Safety Expert (m/f/d) Frankfurt am Main Vollzeit R2562562 Job overview We are seeking an experienced toxicologist who is highly-motivated to work in global research and development project teams. The successful candidate will provide scientific expertise on toxicology and safety pharmacology needs to the project teams and will be responsible for designing and executing safety strategies. The focus will be mainly on immunomodulatory drugs, covering a range of different modalities. Responsibilities Serve as Preclinical Safety Project Team Representative on multi-disciplinary teams, with focus on Research and Development projects Responsible for designing and coordinating multi-disciplinary efforts to support projects progression, i.e.: developing the preclinical safety strategy design and interpretation of toxicity studies conduct of preclinical GLP-safety studies at contract research organizations (CROs) as scientific study monitor review of written safety pharmacology and toxicology reports communication of results to project teams and management authoring of the nonclinical document sections for regulatory documents; Close interaction with multiple partners in pre-clinical safety as well as key stakeholders (Pharmacology, DMPK, Chemistry, Regulatory Affairs, Clinical, Project Leaders & Managers, Pharmacovigilance, etc.) on a daily basis is key and requires excellent communication and negotiation skills Guide issue-resolution teams, where she/he will provide key contribution to hypotheses generation and drive the scientific strategy for toxicology issue resolution in drug discovery and development projects. Ensure high scientific standards and adhering to requested timelines in all aspects of the position Requirements University Degree in veterinary medicine or natural science with academic degree (PhD) >10 years of relevant industry experience in early and late stage drug development projects, preferentially in the role as Preclinical Safety Project Team representative Strong record in drug development covering different modalities (antibodies, nucleic acid therapeutics, small molecules, peptides) Excellent scientific background in immunology, immunotoxicology, and/or safety biomarkers In addition strong background in biochemistry, pharmacology, biology, physiology and pathology Investigative mindset and knowledgeable about state of the art technologies in preclinical safety Knowledgeable about GLP policies and/or regulatory nonclinical testing requirements for pharmaceutical development of biotherapeutics and small molecules Experience as a GLP Study Director and/or as study monitor for studies at contract research organizations (CROs) would be preferred Excellent communication skills, team spirit and proven ability to collaborate transversally in a global organization Additional qualifications as expert in toxicology would be preferred, but not required Our offer: An international work environment, in which you can develop your talent and realize ideas and innovations within a competent team. An attractive, market-oriented salary aligned with your qualifications and including social benefits above average (e.g. company pension plans, health management). An individual and well-structured introduction and training of new employees. You can create your own career path within Sanofi. Your professional and personal development will be supported purposefully. As a globally successful and constantly growing company, Sanofi provides international career paths as well. #LI-GSA Diversity und Inklusion“ sind in den Grundwerten von Sanofi verankert und spiegeln sich in unserer Arbeitsweise wider. Wir respektieren die Vielfalt unserer Belegschaft in Hinsicht auf ihre Herkunft, Erfahrungen und Lebensweisen. Wir erkennen die Bereicherung, die diese Vielfalt birgt, und fördern Inklusion sowie eine Arbeitsumgebung, in der diese Unterschiede sich weiter entwickeln können, zur Stärkung des Lebens unserer Mitarbeiter, Patienten und Kunden. Über uns Sanofi ist ein weltweites Gesundheitsunternehmen, das Menschen bei ihren gesundheitlichen Herausforderungen unterstützt. Mit unseren Impfstoffen beugen wir Erkrankungen vor. Mit innovativen Arzneimitteln lindern wir ihre Schmerzen und Leiden. Wir kümmern uns gleichermaßen um Menschen mit seltenen Erkrankungen wie um die Millionen von Menschen mit einer chronischen Erkrankung. Mit mehr als 100.000 Mitarbeitern in 100 Ländern weltweit übersetzen wir wissenschaftliche Innovation in medizinischen Fortschritt. Sanofi, Empowering Life.